Research

Bacterial pathogens survive under hostile environments and cause many diseases in host. Specifically, bacteria are tolerant to stresses such as antibiotics and host immune response that enable them to survive long term. Our research team are trying to address a question by investigating bacterial pathogens with hosts using biochemical tools, global profiling of RNA, protein and metabolites, and bioinformatic tools:

How do bacteria respond to environmental stress such as antibiotics and immune response?

Mg2+ transporter regulation by FtsH in Salmonella
Mesenteric macrophages control systemic inflammation
ATP-dependent proteolysis and bacterial regrowth
Protective bacterial antigen structure
IscR-mediated morphological change in Acinetobacter baumannii